Parkinson

Parkinson’s disease is a disease characterized by tremor at rest, rigidity, and loss of reflexes bradikinesia postural6, and the pathology of degeneration of pigmented neurons in pars kompakta neuromielanin especially nigra is accompanied by neuronal cell inclusions eusinofilik.
Parkinson’s disease was first introduced in writing in “an essay on the shaking palsy” by James Parkinson in 1817 in London. James Parkinson used the term paralysis agitans or shaking palsy.
Actually this disease there are already thousands of years ago as in ayurvedic, practice and treatment system in India in early 5000 years BC and in the text of the first Chinese Medicine (Neijing) 2500 years ago
Parkinson’s disease usually occurs following Epidemic Encephalitis attacks or because of cerebral atherosclerosis, manganese or carbon monoxide poisoning, trauma to the head, neurosyphilis or cerebrovascular accident.
In North America approximately one million residents affected by this disease, where approximately 1% present in the population aged over 65 years. The incidence in all parts of the city in North America is almost the same. Crude death rate in America in the year 1962 – 1975 of about 1.4 – 1.6% per 100,000 population.
The pathophysiology is known that Parkinson’s disease occurs in neuro-humoral balance disturbances in the basal ganglia, particularly traktur nigrostriatum the extrapyramidal system. Ehringer and Hornykiewiez revealed that the obliteration of neurons in the pars kompakta substansia the dopaminergic nigra is a primary lesion that underlies Parkinson’s disease